Debuffs are almost irrelevant in the game now. Characters, heck entire factions, that are built around applying debuffs are severely gimped. Cleanses everywhere. On hits, on getting hit, just taking a turn cleanses. Not to mention the nifty group cleanses that come with fun bonuses like health gain, tm gain, and reversing your debuffs into buffs. That's considering that you can get past the built in 15% resist chance and Debuff Immunity (I refuse to call it tenacity up because it's not).
A huge mechanic in the game is being minimized and I don't think it can climb out of this hole. In fact, the hole just keeps getting deeper.