I am using Yoda to grant Foresight to all allies during the AGI Gear Challenge, Tier 3. My expectation is that this will grant the party immunity to Opress' big AoE attack but it does not. All characters are still hit and reduced to 1 HP.
Obviously I can't truly confirm this but I'm guessing this behavior is intentional. Otherwise it would trivialize the encounter and no longer be a "challenge".
Note that challenges typically have different mechanics than normal PvP or PvE play.
They may not have the same stats/gear/abilities that we have access to but the fundamental game mechanics should still apply. Foresight is supposed to grant complete immunity to all effects of an attack, is it not? I wasn't aware that there was anything that could bypass it, even if it is a Challenge.
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Note that challenges typically have different mechanics than normal PvP or PvE play.